HuagongsheHuagongshe Chemistry Print Report · For research reference only
p-Toluenesulfonate → HCID 18646530, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | p-Toluenesulfonate | HCID 85570 | — |
| Reactant | HCID 7016379 | HCID 7016379 | — |
| Reactant | HCID 10423016 | HCID 10423016 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 18646530 | HCID 18646530 | 65% |
Reaction Steps
m-(p-Cyanobenzamido)benzoic acid is activated in the same manner as described under a) and coupled with the p-toluenesulphonate of H-Asp(OtBu)OMe in DMF at room temperature. There is isolated 3-(t-butoxycarbonyl)-N-[m-(p-cyanobenzamido)benzoyl]-L-alanine methyl ester in the form of colourless crystals. Yield: 65%, m.p. 83°-84° C. (hexane).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05039805 |
| Source dataset | uspto-grants-1991_08 |
| ORD ID | ord-7806ce1663654cac9a69f5269443b2fe |
| Source note | uspto-grants-1991_08 |