Sodium Hydroxide → HCID 19994209, compound

HRID 2248528Notes

Reaction equation

HRID 2248528 reaction equation
[NH2:1][CH2:2][CH2:3][NH:4][C:5]1[CH:10]=[CH:9][C:8]([N:11]2[C:15](=O)[CH2:14][O:13][CH-]2)=[CH:7][C:6]=1[N+:17]([O-:19])=[O:18].[OH-].[Na+]>C(O)C>[NH2:1][CH2:2][CH2:3][NH:4][C:5]1[CH:10]=[CH:9][C:8]([NH:11][CH2:15][CH2:14][OH:13])=[CH:7][C:6]=1[N+:17]([O-:19])=[O:18]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 178511330HCID 178511330, compound

Product 1

HCID 19994209HCID 19994209, compoundYield 9%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Conditions

Temperature
95 °C

Procedure

0.4 mole (10.64 g) of N-[4-(β-aminoethyl)amino-3-nitrophenyl]oxazolidone, prepared according to Example 10, is added to 27 ml of 3N sodium hydroxide and 11 ml of 96° strength ethanol. After being heated for 45 minutes at 95° C., the solution is poured onto ice, and the precipitate obtained is drained and then washed with iced water. After being dried under vacuum, 0.036 mole (8.7 g) of the expected product is obtained. It melts at 112° C.

Workup

  1. additionthe solution is poured onto ice
  2. customthe precipitate obtained
  3. washwashed with iced water
  4. customAfter being dried under vacuum

Sources & evidence

ORD record
ord-03a76ed7f7bd4d33a1ee5a55bcdca603
Source dataset
uspto-grants-1991_08
Patent number
US05041143

Reaction notes

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