M-Cresol → Benzoic acid, 3-methylphenyl ester

HRID 2248529Notes

Reaction equation

HRID 2248529 reaction equation
[CH:1]1[C:6]([OH:7])=[CH:5][CH:4]=[CH:3][C:2]=1[CH3:8].[C:9](Cl)(=[O:16])[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1>[OH-].[Na+]>[C:9]([O:7][C:6]1[CH:5]=[CH:4][CH:3]=[C:2]([CH3:8])[CH:1]=1)(=[O:16])[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1

Participants

4

Reactant 2

HCID 342M-CresolHCID 7412Benzoyl chloride

Product 1

HCID 69193Benzoic acid, 3-methylphenyl ester

Reagents, catalysts & solvents 1

HCID 14798Sodium HydroxideSolvent

Procedure

Metacresyl benzoate was prepared by vigorously shaking a mixture of metacresol (1 equivalent, 5 grams) and benzoyl chloride (1.2 equivalents, 7.1 grams) in a 10% aqueous solution of sodium hydroxide (100 ml) in a stoppered flask for 15 minutes. The white crystalline solid thus formed was removed by filtration, washed with water and dried to yield metacresyl benzoate.

Workup

  1. customMetacresyl benzoate was prepared
  2. customThe white crystalline solid thus formed
  3. customwas removed by filtration
  4. washwashed with water
  5. customdried

Sources & evidence

ORD record
ord-ba7d5364089d403682484ba65b5e582d
Source dataset
uspto-grants-1991_08
Patent number
US05041169

Reaction notes

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