Methyl iodide → 3-(4-Chloro-1,2,5-thiadiazol-3-yl)-1-methylpyridinium iodide

HRID 2248666Notes

Reaction equation

HRID 2248666 reaction equation
[Cl:1][C:2]1[C:3]([C:7]2[CH:8]=[N:9][CH:10]=[CH:11][CH:12]=2)=[N:4][S:5][N:6]=1.[CH3:13][I:14]>CC(C)=O>[I-:14].[Cl:1][C:2]1[C:3]([C:7]2[CH:8]=[N+:9]([CH3:13])[CH:10]=[CH:11][CH:12]=2)=[N:4][S:5][N:6]=1

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 104881643-Chloro-4-(pyridin-3-yl)-1,2,5-thiadiazole

Product 1

HCID 190753343-(4-Chloro-1,2,5-thiadiazol-3-yl)-1-methylpyridinium iodideYield 100.1%

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

A solution of 3-(4-chloro-1,2,5-thiadiazol-3-yl)pyridine (1.98 g, 10 mmol) and methyl iodide (4.25 g, 30 mmol) in acetone (10 ml) was stirred at room temperature for 16 h. The precipitate was collected by filtration to yield 3.40 g (100%) of the title compound.

Workup

  1. filtrationThe precipitate was collected by filtration

Sources & evidence

ORD record
ord-84d05d29212a4e3e8b6e39b9cf82ccce
Source dataset
uspto-grants-1991_08
Patent number
US05041455

Reaction notes

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