HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfuric Acid → Thiophene-2-thiol, S-acetyl-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | 2-Chlorothiophene | HCID 7299 | — |
| Reactant | Methyl 3-hydroxy-4-methyl-5-methoxythiophene-2-carboxylate | HCID 54710752 | — |
| Reactant | HCID 178418634 | HCID 178418634 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | Thiophene-2-thiol, S-acetyl- | HCID 13133366 | 75% |
Reaction Steps
The chlorothiophene of (e) above (0.016 mol) in 10 ml of acetic acid was added to a solution of 0.9 ml of concentrated sulphuric acid in 10 ml of acetic acid. Whilst stirring, thioacetic acid (0.016 mol) was added and the mixture stood at room temperature for eight hours. Filtration of the precipitate afforded 75% of acetylthiothiophene which was recrystallised from hexane, m.p. 112°-114° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05041461 |
| Source dataset | uspto-grants-1991_08 |
| ORD ID | ord-84c0e2b679d04790a398bf6f9fc5f9b5 |
| Source note | uspto-grants-1991_08 |