反应详情

To a mixture of 2-(acetoxyacetylamino)-6-nitrobenzonitrile (5.7 g) and ethanol (50 ml) are added cyclohexene (10.5 ml) and 10% palladium-carbon (4.7 g). The mixture is refluxed for 20 minutes, and the reaction mixture is cooled to room temperature, and the solid materials are filtered off. The filtrate is distilled under reduced pressure. The residual crude crystals are recrystallized from ethanol to give the title compound (1.2 g) having the following physical properties.

1. temperatureThe mixture is refluxed for 20 minutes
2. filtrationthe solid materials are filtered off
3. distillationThe filtrate is distilled under reduced pressure
4. customThe residual crude crystals are recrystallized from ethanol