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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 224886Generated: October 26, 2026

5-(((2-Aminoethyl)thio)methyl)-N,N-dimethyl-2-furanmethanamine → 2-[2-(5-Dimethylaminomethyl-2-furylmethylthio)ethylamino]-5-methyl-4-pyrimidone

https://huagongshe.com/reaction/224886

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(((2-Aminoethyl)thio)methyl)-N,N-dimethyl-2-furanmethanamineHCID 162203—
Reactant5-Methyl-2-(methylthio)pyrimidin-4(3H)-oneHCID 240575—
SolventPyridineHCID 1049—
Product2-[2-(5-Dimethylaminomethyl-2-furylmethylthio)ethylamino]-5-methyl-4-pyrimidoneHCID 20213282—

Reaction Steps

Reaction of 2-methylthio-5-methyl-4-pyrimidone with one equivalent of 2-(5-dimethylaminomethyl-2-furylmethylthio)ethylamine by boiling under reflux in pyridine for 48 hours gives 2-[2-(5-dimethylaminomethyl-2-furylmethylthio)ethylamino]-5-methyl-4-pyrimidone.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04234588
Source datasetuspto-grants-1980_11
ORD IDord-7b42068a35a74621ab68b41a0c0bab11
Source noteuspto-grants-1980_11