HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 5'-Methyl-4'-methylenespiro[1-azabicyclo[2,2,2]-octane-3,2'-thiolane]
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Ethanol | HCID 702 | — |
| Reactant | 5'-Methylspiro[1-azabicyclo[2,2,2]-octane-3,2'-thiolan]-4'-one | HCID 14852058 | — |
| Product | 5'-Methyl-4'-methylenespiro[1-azabicyclo[2,2,2]-octane-3,2'-thiolane] | HCID 14852064 | — |
Reaction Steps
5'-Methyl-4'-methylenespiro[1-azabicyclo[2.2.2]-octane-3,2'-thiolane] was prepared in much the same manner as in Example 5 by using 5'-methylspiro[1-azabicyclo[2.2.2]-octane-3,2'-thiolan]-4'-one. It was dissolved in ethanol, and then convereted to hydrochloride by addition of ethanolic hydrogen chloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05041549 |
| Source dataset | uspto-grants-1991_08 |
| ORD ID | ord-2e976b15bf284f92a2fc22ebae786651 |
| Source note | uspto-grants-1991_08 |