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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2248874Generated: November 1, 2026

Water → Phenol, 3-(2-quinolinylmethoxy)-

https://huagongshe.com/reaction/2248874

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantResorcinolHCID 5054—
ReactantPotassium CarbonateHCID 11430—
Reactant2-(Chloromethyl)quinoline hydrochlorideHCID 3083823—
SolventDimethylformamideHCID 6228—
ProductPhenol, 3-(2-quinolinylmethoxy)-HCID 10988736—

Reaction Steps

A mixture (0.06 moles) of 2-chloromethylquinoline hydrochloride, (0.06 moles) of 1,3-benzenediol and 18 g of potassium carbonate in 50 ml of dimethylformamide is heated at 70° C. overnight. The reaction mixture is poured into water, and the precipitated product is collected, filtered and dried to give 3-(2-quinolinylmethyloxy)phenol having an m.p. of 151-53° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05041453
Source datasetuspto-grants-1991_08
ORD IDord-2bb32b70c13140cb826e3ab9ffafd52b
Source noteuspto-grants-1991_08