Sodium Methoxide → HCID 12896857, compound

HRID 2248914Notes

Reaction equation

HRID 2248914 reaction equation
C([C@@:4]1([OH:12])[CH2:9][CH2:8][C@H:7]2[CH2:10][O:11][C@@H:5]1[O:6]2)(=O)C.C[O-].[Na+]>CO>[C@@H:5]12[O:11][CH2:10][C@@H:7]([O:6]1)[CH2:8][CH2:9][C@H:4]2[OH:12]

Participants

4

Reactant 2

HCID 10942334Sodium MethoxideHCID 57145868HCID 57145868, compound

Product 1

HCID 12896857HCID 12896857, compoundYield 100.5%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

[C] 25 g of 1,6-anhydro-2-acetyl-3,4-dideoxy-β-D-galactopyranose (6), obtained in the step [B] was dissolved in 100 ml of methanol, forming a solution. A small amount of sodium methoxide was added to the solution. The solution was stirred for one hour at room temperature, causing a reaction therein. Upon the completion the reaction, cation exchange resin was added to the solution, and the solution was stirred for 10 minutes. The insoluble substance was filtered off, and the solvent was distilled off under reduced pressure, whereby 19 g of 1,6-anhydro-3,4-dideoxy-β-D-galactopyranose (7) was obtained at a yield of 100%. This substance exhibited the following physical properties:

Workup

  1. customforming a solution
  2. customa reaction
  3. customUpon the completion the reaction, cation exchange resin
  4. additionwas added to the solution
  5. stirringthe solution was stirred for 10 minutes
  6. filtrationThe insoluble substance was filtered off
  7. distillationthe solvent was distilled off under reduced pressure

Sources & evidence

ORD record
ord-f4b7829dbe7b4802acd934cdb6430a17
Source dataset
uspto-grants-1991_08
Patent number
US05041566

Reaction notes

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