HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrazine hydrate (1:1) → 5-METHOXY-alpha,alpha-DIMETHYL-1H-INDOL-3-YL-ETHANEAMINE
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Reactant | 5-methoxy-3-(2,2-dimethyl-2-nitroethyl)-1H-indole | HCID 12619662 | — |
| Catalyst | Nickel | HCID 935 | — |
| Product | 5-METHOXY-alpha,alpha-DIMETHYL-1H-INDOL-3-YL-ETHANEAMINE | HCID 12619664 | — |
Reaction Steps
The nitro compound produced in Procedure 69C was reduced with Raney nickel and hydrazine hydrate according to the method of Procedure 67D. The structure of the product was confirmed by examination of the NMR spectrum, m.p. 114°-116°, yield 25.8 g. from 31.3 g. of nitro compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04234595 |
| Source dataset | uspto-grants-1980_11 |
| ORD ID | ord-7aa788432e954d24928aaf6ebc401217 |
| Source note | uspto-grants-1980_11 |