1-Tetralone → HCID 53804209, compound

Participants

Reaction Steps

α-Tetralone (26.4 g) and 40 g of 2-[3-(dimethylamino)-propoxy]benzaldehyde are reacted in 180 ml of ethanol in the presence of 1.2 g of potassium hydroxide following the procedure in Example 1A. The product is extracted with ether and the solvent is evaporated to give a viscous residue (67.2 g), which begins to solidify on standing. It is crystallized from a mixture of 120 ml of warm diisopropylether and 120 ml of hexane to give 45.7 g of crystals, melting point 67°-69° C.

Provenance & Evidence