HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2249002Generated: October 31, 2026
Thionyl Chloride → (-)-2-(Pentafluorophenyl)propionyl chloride
https://huagongshe.com/reaction/2249002
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | Benzeneacetic acid, 2,3,4,5,6-pentafluoro-alpha-methyl- | HCID 5743473 | — |
| Product | (-)-2-(Pentafluorophenyl)propionyl chloride | HCID 14651855 | — |
Reaction Steps
A mixture of 4.8 ml of thionyl chloride and 8.10 g of (-)-2-(pentafluorophenyl)propionic acid obtained in Example 4 was stirred for 10 hours at 80° C. Excess thionyl chloride was distilled off under reduced pressure, and the subsequent distillation under reduced pressure gave 6.61 g of (-)-2-(pentafluorophenyl)propionyl chloride having the aforementioned physical properties.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US05041641 |
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| Source dataset | uspto-grants-1991_08 |
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| ORD ID | ord-126257cf85544ef4beb3cfed1c38f8c3 |
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| Source note | uspto-grants-1991_08 |
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