HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2249008Generated: November 2, 2026
Tributylstannane → S(-)-1-(PENTAFLUOROPHENYL)ETHANOL
https://huagongshe.com/reaction/2249008
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Tributylstannane | HCID 5948 | — |
| Reactant | Azobisisobutyronitrile | HCID 6547 | — |
| Reactant | HCID 54517612 | HCID 54517612 | — |
| Product | S(-)-1-(PENTAFLUOROPHENYL)ETHANOL | HCID 6993305 | 66.2% |
Reaction Steps
A mixture of 1.23 g of (R)-(-)-2-chloro-1-(pentafluorophenyl)ethanol obtained in Example 8, 1.60 ml of tributyltin hydride, and 16 mg of AIBN was stirred for eight hours at 80° C. After completion of reaction, the reaction mixture was purified by silica gel column chromatography to give 0.7 g of (S)-(-)-1-(pentafluorophenyl)-ethanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US05041641 |
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| Source dataset | uspto-grants-1991_08 |
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| ORD ID | ord-f6c1ed12612047a2aac580c204f1042d |
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| Source note | uspto-grants-1991_08 |
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