2,3-Dihydroxybutanedioic Acid → HCID 86737340, compound

HRID 224912Notes

Reaction equation

HRID 224912 reaction equation
[CH3:1][CH2:2][C@H:3]1[O:21][C:19](=[O:20])[CH2:18][C@@H:17]([OH:22])[C@H:16]([CH3:23])[C@@H:15]([O:24][C@@H:25]2[O:30][C@H:29]([CH3:31])[CH2:28][C@H:27]([N:32]([CH3:34])[CH3:33])[C@H:26]2[OH:35])[C@@H:14]([CH2:36][CH:37]=[O:38])[CH2:13][C@@H:12]([CH3:39])[C:10](=[O:11])[CH:9]=[CH:8][C@:6]2([CH3:40])[O:7][C@H:5]2[C@@H:4]1[CH3:41].[C:42]([OH:51])(=[O:50])[CH:43]([CH:45]([C:47]([OH:49])=[O:48])[OH:46])[OH:44].O>C(OCC)C.C(O)C>[CH3:1][CH2:2][C@H:3]1[O:21][C:19](=[O:20])[CH2:18][C@@H:17]([OH:22])[C@H:16]([CH3:23])[C@@H:15]([O:24][C@@H:25]2[O:30][C@H:29]([CH3:31])[CH2:28][C@H:27]([N:32]([CH3:33])[CH3:34])[C@H:26]2[OH:35])[C@@H:14]([CH2:36][CH:37]=[O:38])[CH2:13][C@@H:12]([CH3:39])[C:10](=[O:11])[CH:9]=[CH:8][C@:6]2([CH3:40])[O:7][C@H:5]2[C@@H:4]1[CH3:41].[C:47]([CH:45]([CH:43]([C:42]([O-:51])=[O:50])[OH:44])[OH:46])([O-:49])=[O:48]

Participants

6

Reactant 3

HCID 8752,3-Dihydroxybutanedioic AcidHCID 962WaterHCID 6537204Rosaramicin

Product 1

HCID 86737340HCID 86737340, compound

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 3283Diethyl EtherSolvent

Procedure

Dissolve 1 gm of rosaramicin in 50 ml of diethyl ether; add a solution of 250 mg of tartaric acid in 1.5 ml of ethanol. Stir the resulting mixture for about 15 minutes, then filter the precipitated salt. Wash the precipitate with diethyl ether; dry the precipitate and obtain thereby the title product, m.p. 129°-134° C., [α]D20 =-12° (C=0.3% water).

Workup

  1. filtrationfilter the precipitated salt
  2. washWash the precipitate with diethyl ether
  3. customdry the precipitate
  4. customobtain

Sources & evidence

ORD record
ord-0afc1159686244c682fd8bacb0471118
Source dataset
uspto-grants-1980_11
Patent number
US04234690

Reaction notes

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