HCID 19995524, compound → HCID 19995517, compound

Participants

Reaction Steps

A solution of 3-tert-butoxycarbonylamino-1,2,3,4-tetrahydro-2-naphthalenol (1.05 g) in acetic acid (100 ml) was hydrogenated over platinum oxyde (121 mg) under pressure (5.5.6 bars) at room temperature for 3 days. The catalyst was filtered and the solvent was evaporated under vacuum. The residue was purified by chromatography on silica gel [140 g, elution with ethyl acetate:cyclohexane, 2:8 (0.7 1) and 5:7 (1 1)] to afford the title compound as an oil (915 mg).

Provenance & Evidence