Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Isobutanol | HCID 6560 | — |
| Reactant | Sodium | HCID 5360545 | — |
| Reactant | 3-Chloro-4-(pyridin-3-yl)-1,2,5-thiadiazole | HCID 10488164 | — |
| Product | HCID 19075496 | HCID 19075496 | — |
Reaction Steps
To a solution of sodium (230 mg, 10 mmol) in isobutanol (20 ml) was added 3-(4-chloro-1,2,5-thiadiazol-3-yl)pyridine (490 mg, 2.5 mmol). The mixture was stirred at 50° C. for 3 h and evaporated. The residue was dissolved in water and extracted with methylene chloride. The combined organic phases were dried and evaporated to give the wanted compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05043345 |
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| Source dataset | uspto-grants-1991_08 |
|---|
| ORD ID | ord-e16934ab5c7645bcabaf2ecfe8204cdb |
|---|
| Source note | uspto-grants-1991_08 |
|---|
