Methyl iodide → 3-(4-Hexyloxy-1,2,5-thiadiazol-3-yl)-1-methylpyridinium iodide

HRID 2249181Notes

Reaction equation

HRID 2249181 reaction equation
[CH3:1][I:2].[CH2:3]([O:9][C:10]1[C:11]([C:15]2[CH:16]=[N:17][CH:18]=[CH:19][CH:20]=2)=[N:12][S:13][N:14]=1)[CH2:4][CH2:5][CH2:6][CH2:7][CH3:8]>CC(C)=O>[I-:2].[CH2:3]([O:9][C:10]1[C:11]([C:15]2[CH:16]=[N+:17]([CH3:1])[CH:18]=[CH:19][CH:20]=2)=[N:12][S:13][N:14]=1)[CH2:4][CH2:5][CH2:6][CH2:7][CH3:8]

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 151801353-(4-(Hexyloxy)-1,2,5-thiadiazol-3-yl)pyridine

Product 1

HCID 189409483-(4-Hexyloxy-1,2,5-thiadiazol-3-yl)-1-methylpyridinium iodide

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

A mixture of methyl iodide (0.5 ml, 7.5 mmol) and 3-(4-hexyloxy-1,2,5-thiadiazol-3-yl)pyridine (658 mg, 2.5 mmol) in acetone (5 ml) was stirred at room temperature for 18h. The title compound precipitated from the solution and was collected by filtration to yield 0.81 g (80%).

Workup

  1. customThe title compound precipitated from the solution
  2. filtrationwas collected by filtration
  3. customto yield 0.81 g (80%)

Sources & evidence

ORD record
ord-de4a5909bf8547238c854d884c6c7fad
Source dataset
uspto-grants-1991_08
Patent number
US05043345

Reaction notes

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