Methyl iodide → HCID 19075336, compound

HRID 2249186Notes

Reaction equation

HRID 2249186 reaction equation
[CH3:1][I:2].[CH2:3]([O:6][C:7]1[C:8]([C:12]2[CH:13]=[N:14][CH:15]=[CH:16][CH:17]=2)=[N:9][S:10][N:11]=1)[C:4]#[CH:5]>CC(C)=O>[I-:2].[CH2:3]([O:6][C:7]1[C:8]([C:12]2[CH:13]=[N+:14]([CH3:1])[CH:15]=[CH:16][CH:17]=2)=[N:9][S:10][N:11]=1)[C:4]#[CH:5]

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 19075253HCID 19075253, compound

Product 1

HCID 19075336HCID 19075336, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

A mixture of methyl iodide (0.45 ml, 7.2 mmol) and 3-(4-propargyloxy-1,2,5-thiadiazol-3-yl)pyridine (430 mg, 2.4 mmol) in acetone (5 ml) was stirred at room temperature for 18 h. The title compound precipitated from the solution and was collected by filtration to yield 0.58 g (67%).

Workup

  1. customThe title compound precipitated from the solution
  2. filtrationwas collected by filtration
  3. customto yield 0.58 g (67%)

Sources & evidence

ORD record
ord-8748acebd9d74755a06ceda93000a8a2
Source dataset
uspto-grants-1991_08
Patent number
US05043345

Reaction notes

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