Methyl iodide → 3-(3-Amino-1,2,5-oxadiazol-4-yl)-1-methylpyridinium iodide

HRID 2249190Notes

Reaction equation

HRID 2249190 reaction equation
[NH2:1][C:2]1[C:6]([C:7]2[CH:8]=[N:9][CH:10]=[CH:11][CH:12]=2)=[N:5][O:4][N:3]=1.[CH3:13][I:14]>CC(C)=O>[I-:14].[NH2:1][C:2]1[C:6]([C:7]2[CH:8]=[N+:9]([CH3:13])[CH:10]=[CH:11][CH:12]=2)=[N:5][O:4][N:3]=1

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 14155234-Pyridin-3-yl-1,2,5-oxadiazol-3-amine

Product 1

HCID 190753223-(3-Amino-1,2,5-oxadiazol-4-yl)-1-methylpyridinium iodide

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

To a solution of 3-(3-amino-1,2,5-oxadiazol-4-yl)pyridine (870 mg, 5.3 mmmol) in acetone (20 ml) was added methyl iodide (990 ul, 16 mmol) and the reaction mixture was stirred over night at room temperature. The title compound precipitated and was collected by filtration (1.1 g, 69%).

Workup

  1. customThe title compound precipitated
  2. filtrationwas collected by filtration (1.1 g, 69%)

Sources & evidence

ORD record
ord-498fc95078054af486364defc57aacd5
Source dataset
uspto-grants-1991_08
Patent number
US05043345

Reaction notes

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