Benzene → HCID 19994130, compound

Participants

Reaction Steps

A reaction vessel equipped with a thermometer, a stirrer and a condenser having a water separator was charged with 133 g of diisopropanolamine, 100 g of benzene, 120 g of methyl isobutyl ketone and p-toluenesulfonic acid. The content was heated to reflux and reacted for another 5 hours with removing water. Benzene was removed under a reduced pressure and then distilled at 75° to 79° C./1 mmHg to obtain 152 g of 2-methyl-2-isobutyl-3-(2-hydroxypropyl)-5-methyloxazolidine.

Provenance & Evidence