HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 7-Hydroxy-4-(1-naphthyl)coumarin
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Resorcinol | HCID 5054 | — |
| Reactant | Ethyl 3-(naphthalen-8-yl)-3-oxopropanoate | HCID 2760157 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 7-Hydroxy-4-(1-naphthyl)coumarin | HCID 23330744 | — |
Reaction Steps
A solution of resorcinol (4.84 g., 0.041 moles) and ethyl 1-naphthoylacetate (10 g., 0.041 moles) in ethanol (50 ml.) was saturated with hydrogen chloride at room temperature (cooling with ice/water) and left to stand in s stoppered flask for 24 hours. The solution was filtered to give the required coumarin as an orange solid (7.8 g., 66%, m.p. 292°-295° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04234726 |
| Source dataset | uspto-grants-1980_11 |
| ORD ID | ord-13d242ac9bd54a34b60200d1f73a5c94 |
| Source note | uspto-grants-1980_11 |