Methyl 4-methylbenzoate → Methyl 4-(bromomethyl)benzoate

Participants

Reaction Conditions

Reaction Steps

To a mixture of methyl-p-toluate (180 g, 1.2 mol) and N-bromosuccimide (235 g, 1.32 mol) in CCl4 (2 L) was added in portion benzoyl peroxide (18 g, 0.1 times) at 50° C. The mixture was refluxed for 5 h. Then the mixture was allowed to cool down to 40° C. and the solid was filtered off. The filtrate was concentrated to give 4-methoxy carbonyl benzyl bromide (252 g, 91%) as light yellow liquid.

Provenance & Evidence