HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(4-chlorobenzyl)-6-(2,3-dihydro-1-benzofuran-5-yl)-4-methanesulfonyloxymethyl-2H-pyridazin-3-one → 4-carboxy-2-(4-chlorocinnamyl)-6-(2,3-dihydro-1-benzofuran-5-yl)-2H-pyridazin-3-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(4-chlorobenzyl)-6-(2,3-dihydro-1-benzofuran-5-yl)-4-methanesulfonyloxymethyl-2H-pyridazin-3-one | HCID 23094103 | — |
| Reactant | HCID 23094117 | HCID 23094117 | — |
| Reactant | p-Chlorocinnamyl chloride | HCID 53728250 | — |
| Product | 4-carboxy-2-(4-chlorocinnamyl)-6-(2,3-dihydro-1-benzofuran-5-yl)-2H-pyridazin-3-one | HCID 69308880 | 44.4% |
Reaction Steps
The general procedure of Example 1 (3) was carried out by use of 6-(2,3-dihydro-1-benzofuran-5-yl)-4-methoxycarbonyl-2H-pyridazin-3-one and 4-chlorocinnamyl chloride, to thereby yield the title compound as an orange powder (yield: 44.4%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07314877B2 |
| Source dataset | uspto-grants-2008_01 |
| ORD ID | ord-6b465427e86e4622bcbd46b317d3a587 |
| Source note | uspto-grants-2008_01 |