2-Chlorobenzyl chloride → HCID 23094122, compound

HRID 2249432Notes

Reaction equation

HRID 2249432 reaction equation
[Cl:1][C:2]1C=C[C:5]([CH2:8][CH2:9][CH2:10][N:11]2[C:16](=[O:17])[C:15]([CH2:18][O:19]S(C)(=O)=O)=[CH:14][C:13]([C:24]3[CH:25]=[CH:26][C:27]4[O:31][CH2:30][CH2:29][C:28]=4[CH:32]=3)=[N:12]2)=[CH:4][CH:3]=1.[O:33]1C2C=CC(C3C=C(C(OC)=O)C(=O)NN=3)=CC=2CC1.ClC1C=CC=CC=1CCl>>[C:18]([C:15]1[C:16](=[O:17])[N:11]([CH2:10][C:9]2[CH:8]=[CH:5][CH:4]=[CH:3][C:2]=2[Cl:1])[N:12]=[C:13]([C:24]2[CH:25]=[CH:26][C:27]3[O:31][CH2:30][CH2:29][C:28]=3[CH:32]=2)[CH:14]=1)([OH:33])=[O:19]

Participants

4

Reactant 3

HCID 119062-Chlorobenzyl chlorideHCID 23094117HCID 23094117, compoundHCID 23094140HCID 23094140, compound

Product 1

HCID 23094122HCID 23094122, compound

Procedure

The general procedure of Example 1 (3) was carried out by use of 6-(2,3-dihydro-1-benzofuran-5-yl)-4-methoxycarbonyl-2H-pyridazin-3-one and 2-chlorobenzyl chloride, to thereby yield the title compound as yellow needle-like crystal (yield: 75.0%).

Sources & evidence

ORD record
ord-c8719191448d4a47a049f1bff6fcbe4c
Source dataset
uspto-grants-2008_01
Patent number
US07314877B2

Reaction notes

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