HCID 58670138, compound → HCID 58670125, compound

Participants

Reaction Steps

A solution of 1L (145 mg, 0.287 mmol) in TFA (1 mL) and CH2Cl2 (1 mL) was stirred at RT for 1 h. After this time, no starting material was detected by LC-MS. The reaction was concentrated under reduced pressure. The resulting residue was diluted with EtOAc (40 mL) and washed with saturated aqueous NaHCO3 (20 mL). The aqueous layer was extracted with EtOAc (20 mL×2). The combined organic layers were washed with saturated NaCl, dried over Na2SO4, filtered and concentrated to give the title compound as a white solid (110 mg, 100%). LC/MS (method A): retention time=3.09 min, (M+H)+=374.

Provenance & Evidence