Methanol → HCID 53674563, compound

Participants

Reaction Steps

12.78 grams of 2-bromo-6-chlorohexanoic acid methyl ester, 6.08 grams of potassium cyanate and 2.72 grams of methanol were heated under powerful stirring in 70 ml of DMF for 1 hour. The reaction mixture was worked up in the manner described in Example 1. There were obtained 6.29 grams (50.3%) of 6-chloro-2-methoxycarbonylaminohexanoic acid methyl ester with boiling point of 113° C./0.0026 mbar.

Provenance & Evidence