huagongshe.com
HRID2249757

反应详情

EQUATION

反应方程式

HRID 2249757 的结构方程式

REACTANTS

反应物

2
结构：NC1CCNCC1
HCID424361

4-Aminopiperidine

C5H12N2

结构：CS(=O)(=O)c1nc(-c2ccccc2Cl)c2ccc(=O)n(-c3ccccc3Cl)c2n1
HCID10225578

未命名化合物

PRODUCTS

生成物

1
结构：O=c1ccc2c(-c3ccccc3Cl)nc(NC3CCNCC3)nc2n1-c1ccccc1Cl
HCID59639551

未命名化合物

PROCEDURE

实验过程

The product of Example 47, and piperidin-4-ylamine were reacted by the procedure of Example 60 to afford the title compound 4,8-bis-(2-chloro-phenyl)-2-(piperidin-4-ylamino)-8H-pyrido[2,3-d]pyrimidin-7-one. 1H-NMR (CDCl3) δ 1.21 (m, 2H), 1.84 (m, 2H), 2.38 (m, 2H), 3.01 (m, 2H), 3.30 (m, 1H), 5.36 (s, 1H), 6.40 (d, 1H, J=9.8 Hz), 7.20-7.62 (m, 9H). LC MS (m/e)=466 (MH+).