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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2249762Generated: October 29, 2026

Glycine ethyl ester → HCID 59639615, compound

https://huagongshe.com/reaction/2249762

Reaction equation

Participants

RoleNameHCIDCharge
ReactantGlycine ethyl esterHCID 12176—
Reactant4,8-bis-(2-chloro-phenyl)-2-methanesulfonyl-8H-pyrido[2,3-d]pyrimidin-7-oneHCID 10225578—
ProductHCID 59639615HCID 59639615—

Reaction Steps

The product of Example 47, and ethyl glycinate were reacted by the procedure of Example 60 to afford the title compound [4,8-bis-(2-chloro-phenyl)-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidin-2-ylamino]-acetic acid ethyl ester. 1H-NMR (CDCl3) δ 1.21 (m, 3H), 3.59 (m, 2H), 4.12 (m, 2H), 5.91 (br s, 1H), 6.41 (m, 2H), 7.25-7.62 (m, 9H). LC MS (m/e)=469 (M+). Rt=2.12 min

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07314881B2
Source datasetuspto-grants-2008_01
ORD IDord-8ad4416a03504806aabb88e40b0b3b3d
Source noteuspto-grants-2008_01