HuagongsheHuagongshe Chemistry Print Report · For research reference only
Glycine ethyl ester → HCID 59639615, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Glycine ethyl ester | HCID 12176 | — |
| Reactant | 4,8-bis-(2-chloro-phenyl)-2-methanesulfonyl-8H-pyrido[2,3-d]pyrimidin-7-one | HCID 10225578 | — |
| Product | HCID 59639615 | HCID 59639615 | — |
Reaction Steps
The product of Example 47, and ethyl glycinate were reacted by the procedure of Example 60 to afford the title compound [4,8-bis-(2-chloro-phenyl)-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidin-2-ylamino]-acetic acid ethyl ester. 1H-NMR (CDCl3) δ 1.21 (m, 3H), 3.59 (m, 2H), 4.12 (m, 2H), 5.91 (br s, 1H), 6.41 (m, 2H), 7.25-7.62 (m, 9H). LC MS (m/e)=469 (M+). Rt=2.12 min
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07314881B2 |
| Source dataset | uspto-grants-2008_01 |
| ORD ID | ord-8ad4416a03504806aabb88e40b0b3b3d |
| Source note | uspto-grants-2008_01 |