HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl mercaptan → (R)-3-Benzylsulfanyl-2-hydroxy-propionic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl mercaptan | HCID 7509 | — |
| Reactant | Methyl (2S)-2-oxiranecarboxylate | HCID 10942355 | — |
| Product | (R)-3-Benzylsulfanyl-2-hydroxy-propionic acid methyl ester | HCID 59639322 | 92% |
Reaction Steps
This reaction was performed as previously described by Deechongkit, S.; You, S.-L.; Kelly, J. W. Org. Lett. 2004, 6, 497, using (S)-Methylglycidate 110a and Benzyl mercaptan. (R)-3-Benzylsulfanyl-2-hydroxy-propionic acid methyl ester 110b (7.41 g, 31.41 mmol, 92%) was isolated as a viscous oil: MS calcd. for C11H14O3S (M+H+) 227.1. found 227.3.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07314872B2 |
| Source dataset | uspto-grants-2008_01 |
| ORD ID | ord-6488fa0568054c73b3ba49af5256f658 |
| Source note | uspto-grants-2008_01 |