HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium Hydroxide → (R)-3-Benzylsulfanyl-2-hydroxy-propionic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium Hydroxide | HCID 3939 | — |
| Reactant | (R)-3-Benzylsulfanyl-2-hydroxy-propionic acid methyl ester | HCID 59639322 | — |
| Product | (R)-3-Benzylsulfanyl-2-hydroxy-propionic acid | HCID 10059030 | 46% |
Reaction Steps
This reaction was performed as previously described by Deechongkit, S.; You, S.-L.; Kelly, J. W. Org. Lett. 2004, 6, 497, using (R)-3-Benzylsulfanyl-2-hydroxy-propionic acid methyl ester 110b and lithium hydroxide. (R)-3-Benzylsulfanyl-2-hydroxy-propionic acid 110c (3.08 g, 14.51 mmol, 46%) was isolated as a viscous oil: MS calcd. for C10H12O3S (M+Na+) 235.1. found 235.3.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07314872B2 |
| Source dataset | uspto-grants-2008_01 |
| ORD ID | ord-bcb8eaa4c4504401886fac377227fe7a |
| Source note | uspto-grants-2008_01 |