3-(1,2-Dibromo-2,2-dichloroethyl)-2,2-dimethylcyclopropanecarboxylic acid → [3-(4-Fluorobenzyl)-1-pyrrolyl]methyl 3-(1,2-dibromo-2,2-dichloroethyl)-2,2-dimethylcyclopropanecarboxylate
Reaction equation
[Br:1][CH:2]([CH:7]1[CH:9]([C:10]([OH:12])=[O:11])[C:8]1([CH3:14])[CH3:13])[C:3]([Br:6])([Cl:5])[Cl:4].[F:15][C:16]1[CH:29]=[CH:28][C:19]([CH2:20][C:21]2[CH:25]=[CH:24][N:23]([CH2:26]O)[CH:22]=2)=[CH:18][CH:17]=1>>[Br:1][CH:2]([CH:7]1[CH:9]([C:10]([O:12][CH2:26][N:23]2[CH:24]=[CH:25][C:21]([CH2:20][C:19]3[CH:18]=[CH:17][C:16]([F:15])=[CH:29][CH:28]=3)=[CH:22]2)=[O:11])[C:8]1([CH3:14])[CH3:13])[C:3]([Br:6])([Cl:4])[Cl:5]Participants
3
Procedure
Following the procedure of Example 1, 3-(1,2-dibromo-2,2-dichloroethyl)-2,2-dimethylcyclopropanecarboxylic acid is reacted with [3-(4-fluorobenzyl)-1-pyrrolyl]methanol to give the final product [3-(4-fluorobenzyl)-1-pyrrolyl]methyl 3-(1,2-dibromo-2,2-dichloroethyl)-2,2-dimethylcyclopropanecarboxylate.
Sources & evidence
- ORD record
- ord-57a3d30b68a94e00b0891cd9a163ecbb
- Source dataset
- uspto-grants-1980_11
- Patent number
- US04235777
Reaction notes
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