Hydrochloric Acid → HCID 50878170, compound

Participants

Reaction Steps

A mixture of the imine of ρ-chlorobenzaldehyde and benzylamine (44 g) and phosphorous acid (15.7 g) was heated with stirring. The mixture became liquid and homogeneous at 75°-80° and at 100°-115° reaction commenced raising the temperature to 140°-150°. Upon cooling the reaction mass set to a glass which was dissolved in aqueous sodium carbonate solution. Addition of hydrochloric acid precipitated a white solid which upon drying yielded N-benzyl α-amino ρ-chlorobenzylphosphonic acid, mp 226°-30°, 52 g. ##STR30##

Provenance & Evidence