HCID 23328879, compound → HCID 23328854, compound

HRID 225046Notes

Reaction equation

HRID 225046 reaction equation
[I:1][C:2]1[CH:3]=[CH:4][C:5]2[CH:11]=[CH:10][C:9]3[CH:12]=[CH:13][C:14]([N+:16]([O-])=O)=[CH:15][C:8]=3[C:7](=[O:19])[C:6]=2[CH:20]=1>C(O)(=O)C>[NH2:16][C:14]1[CH:13]=[CH:12][C:9]2[CH:10]=[CH:11][C:5]3[CH:4]=[CH:3][C:2]([I:1])=[CH:20][C:6]=3[C:7](=[O:19])[C:8]=2[CH:15]=1

Participants

3

Reactant 1

HCID 23328879HCID 23328879, compound

Product 1

HCID 23328854HCID 23328854, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

3-Iodo-7-nitro-5H-dibenzo[a,d]cyclohepten-5-one (23.4 g., 0.062 mole) in 140 ml. of glacial acetic acid is heated to 90° and treated with stannous chloride dihydrate (52 g., 0.23 mole), added in portions as the solid. The temperature of the mixture is maintained between 95° and 100° throughout the addition and for 10-15 minutes thereafter. The mixture is then cooled to ca 50° and poured into 1 liter of ice water.

Workup

  1. additionadded in portions as the solid
  2. temperatureThe temperature of the mixture is maintained between 95° and 100° throughout the addition and for 10-15 minutes
  3. temperatureThe mixture is then cooled to ca 50°

Sources & evidence

ORD record
ord-bfe56d639a9b4724b09de2fa8ed280fb
Source dataset
uspto-grants-1980_11
Patent number
US04235820

Reaction notes

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