Vinyl chloroformate → HCID 23328885, compound

HRID 225049Notes

Reaction equation

HRID 225049 reaction equation
[CH3:1][N:2]([CH2:4][CH2:5][CH2:6][CH:7]1[C:13]2[CH:14]=[C:15]([I:18])[CH:16]=[CH:17][C:12]=2[CH:11]=[CH:10][C:9]2[CH:19]=[CH:20][C:21]([I:23])=[CH:22][C:8]1=2)C.[Cl:24]C(OC=C)=O>C1C=CC=CC=1>[ClH:24].[CH3:1][NH:2][CH2:4][CH2:5][CH2:6][CH:7]1[C:8]2[CH:22]=[C:21]([I:23])[CH:20]=[CH:19][C:9]=2[CH:10]=[CH:11][C:12]2[CH:17]=[CH:16][C:15]([I:18])=[CH:14][C:13]1=2

Participants

4

Reactant 2

HCID 78808Vinyl chloroformateHCID 23328867HCID 23328867, compound

Product 1

HCID 23328885HCID 23328885, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent2×

Procedure

N,N-Dimethyl-3-(3,7-diiodo-5H-dibenzo[a,d]cyclohepten-5-yl)propylamine (7.3 g., 0.014 mole) in 30 ml. of benzene is added dropwise to 1.6 g. (0.015 mole) of vinyl chloroformate in 25 ml. of benzene stirred in an ice bath. Upon completion of the addition, the mixture is stirred at 30° for 15 minutes, and at 50°, another 60 minutes. The clear, pale yellow supernatant is decanted from the residual gum, filtered, and evaporated in vacuo to a yellow oil.

Workup

  1. additionUpon completion of the addition
  2. customat 50°
  3. customanother 60 minutes
  4. customThe clear, pale yellow supernatant is decanted from the residual gum
  5. filtrationfiltered
  6. customevaporated in vacuo to a yellow oil

Sources & evidence

ORD record
ord-ccb9a2c898ee49b98ae0d831129cff19
Source dataset
uspto-grants-1980_11
Patent number
US04235820

Reaction notes

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