HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → N-(2-Amino-3-carboxyphenyl)-N'-(4-methyl-3-thienyl)thiourea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | 2,3-Diaminobenzoic acid | HCID 198069 | — |
| Reactant | 3-Isothiocyanato-4-methylthiophene | HCID 22139827 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | N-(2-Amino-3-carboxyphenyl)-N'-(4-methyl-3-thienyl)thiourea | HCID 22139830 | — |
Reaction Steps
is obtained analogously to the procedure described in example 25 a) from 3-carboxy-1,2-diaminobenzene and 4-methyl-3-thienyl isothiocyanate in anhydrous THF, followed by medium-pressure chromatography on silica gel using a mixture of 12 parts of methylene chloride and 1 part of methanol. Amorphous product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07317033B2 |
| Source dataset | uspto-grants-2008_01 |
| ORD ID | ord-6ed7a73ca50c4c19b0b10633a0581f29 |
| Source note | uspto-grants-2008_01 |