Potassium Iodide → 5-(3-Iodopropyl)-3-iodo-5H-dibenzo[a,d]cycloheptene

HRID 225052Notes

Reaction equation

HRID 225052 reaction equation
[I-:1].[K+].C(O[CH2:6][CH2:7][CH2:8][CH:9]1[C:15]2[CH:16]=[C:17]([I:20])[CH:18]=[CH:19][C:14]=2[CH:13]=[CH:12][C:11]2[CH:21]=[CH:22][CH:23]=[CH:24][C:10]1=2)C>>[I:1][CH2:6][CH2:7][CH2:8][CH:9]1[C:15]2[CH:16]=[C:17]([I:20])[CH:18]=[CH:19][C:14]=2[CH:13]=[CH:12][C:11]2[CH:21]=[CH:22][CH:23]=[CH:24][C:10]1=2

Participants

3

Reactant 2

HCID 4875Potassium IodideHCID 123351515-(3-Ethoxypropyl)-3-iodo-5H-dibenzo[a,d]cycloheptene

Product 1

HCID 233288575-(3-Iodopropyl)-3-iodo-5H-dibenzo[a,d]cycloheptene

Procedure

Phosphorus pentoxide (1.28 g.) and concentrated (85%) phosphoric acid (2.7 ml.) are mixed well and cooled to room temperature. Potassium iodide (6.6 g., 0.04 mole), finely powdered, and 5-(3-ethoxypropyl)-3-iodo-5H-dibenzo[a,d]cycloheptene (4.0 g., 0.01 mole) are added and the mixture stirred and heated in an oil bath at 110° for 16 hours.

Workup

  1. concentrationPhosphorus pentoxide (1.28 g.) and concentrated (85%) phosphoric acid (2.7 ml.)
  2. additionare mixed well
  3. temperatureheated in an oil bath at 110° for 16 hours

Sources & evidence

ORD record
ord-a9bdfbc485744099879bcf71373afdd7
Source dataset
uspto-grants-1980_11
Patent number
US04235820

Reaction notes

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