Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 5-Chloronicotinate | HCID 6994321 | — |
| Product | 5-Chloronicotinic acid | HCID 247986 | 6.5% |
Reaction Steps
To 5-chloronicotinate (105 g) was added 1N NaOH (84.9 mL) at ambient temperature. The mixture was heated at 60° C. for 1 hour. The reaction mixture was adjusted to pH 4-5 with HCl. The precipitate was filtered to give 5-chloronicotinic acid (6.9 g) a colorless solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07317009B2 |
|---|
| Source dataset | uspto-grants-2008_01 |
|---|
| ORD ID | ord-34bba7a5d5974ee7bced1a5f103caac5 |
|---|
| Source note | uspto-grants-2008_01 |
|---|
