Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2250664Generated: October 26, 2026

4,6-Difluoro-1,3-benzothiazol-2-amine → 5-Methyl-thiophene-2-carboxylic acid (4,6-difluoro-benzothiazol-2-yl)-amide

https://huagongshe.com/reaction/2250664

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4,6-Difluoro-1,3-benzothiazol-2-amineHCID 737406—
Reactant5-Methylthiophene-2-carbonyl chlorideHCID 2760083—
Product5-Methyl-thiophene-2-carboxylic acid (4,6-difluoro-benzothiazol-2-yl)-amideHCID 86584897—

Reaction Steps

Using 2-amino-4,6-difluoro-benzothiazole and 5-methyl-thiophene-carboxylicacid chloride the title compound was prepared as a yellow solid (74% yield), MS: m/e=310 (M+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07317007B2
Source datasetuspto-grants-2008_01
ORD IDord-3fdcd24600204d3c998fbd7bafe63d72
Source noteuspto-grants-2008_01