4-Fluorobenzoyl chloride → HCID 9925040, compound

HRID 2250676Notes

Reaction equation

HRID 2250676 reaction equation
[CH3:1][O:2][C:3]([C:5]1[C:13]2[S:12][C:11]([NH2:14])=[N:10][C:9]=2[C:8]([O:15][CH3:16])=[CH:7][CH:6]=1)=[O:4].[F:17][C:18]1[CH:26]=[CH:25][C:21]([C:22](Cl)=[O:23])=[CH:20][CH:19]=1>>[CH3:1][O:2][C:3]([C:5]1[C:13]2[S:12][C:11]([NH:14][C:22](=[O:23])[C:21]3[CH:25]=[CH:26][C:18]([F:17])=[CH:19][CH:20]=3)=[N:10][C:9]=2[C:8]([O:15][CH3:16])=[CH:7][CH:6]=1)=[O:4]

Participants

3

Reactant 2

HCID 678794-Fluorobenzoyl chlorideHCID 86584903HCID 86584903, compound

Product 1

HCID 9925040HCID 9925040, compound

Procedure

Using 2-amino-4-methoxy-benzothiazole-7-carboxylic acid methyl ester and 4-fluoro-benzoyl chloride the title compound was obtained as a white solid (91% yield), MS: m/e=361.1 (M+H+).

Sources & evidence

ORD record
ord-f852538f2966490bb3131b36ee653858
Source dataset
uspto-grants-2008_01
Patent number
US07317007B2

Reaction notes

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