4-Fluorobenzoyl chloride → HCID 22283303, compound

HRID 2250681Notes

Reaction equation

HRID 2250681 reaction equation
[CH3:1][O:2][C:3]1[C:8]2[N:9]=[C:10]([NH2:12])[S:11][C:7]=2[C:6]([CH2:13][N:14]2[CH2:19][CH2:18][O:17][CH2:16][CH2:15]2)=[CH:5][CH:4]=1.[F:20][C:21]1[CH:29]=[CH:28][C:24]([C:25](Cl)=[O:26])=[CH:23][CH:22]=1>N1C=CC=CC=1>[F:20][C:21]1[CH:29]=[CH:28][C:24]([C:25]([NH:12][C:10]2[S:11][C:7]3[C:6]([CH2:13][N:14]4[CH2:19][CH2:18][O:17][CH2:16][CH2:15]4)=[CH:5][CH:4]=[C:3]([O:2][CH3:1])[C:8]=3[N:9]=2)=[O:26])=[CH:23][CH:22]=1

Participants

4

Reactant 2

HCID 678794-Fluorobenzoyl chlorideHCID 22283216HCID 22283216, compound

Product 1

HCID 22283303HCID 22283303, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

Using 4-methoxy-7-morpholin-4-ylmethyl-benzothiazol-2-ylamine and 4-fluoro-benzoyl chloride in pyridine the title compound was obtained as a yellow solid (44% yield), MS: m/e=402.4 (M+H+).

Sources & evidence

ORD record
ord-548c0234be9c4930befefcf17f2a00c4
Source dataset
uspto-grants-2008_01
Patent number
US07317007B2

Reaction notes

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