5-Methylthiophene-2-carbonyl chloride → HCID 86584905, compound

HRID 2250682Notes

Reaction equation

HRID 2250682 reaction equation
[CH3:1][O:2][C:3]1[C:8]2[N:9]=[C:10]([NH2:12])[S:11][C:7]=2[C:6]([CH2:13][N:14]2[CH2:19][CH2:18][O:17][CH2:16][CH2:15]2)=[CH:5][CH:4]=1.[CH3:20][C:21]1[S:25][C:24]([C:26](Cl)=[O:27])=[CH:23][CH:22]=1>N1C=CC=CC=1>[CH3:1][O:2][C:3]1[C:8]2[N:9]=[C:10]([NH:12][C:26]([C:24]3[S:25][C:21]([CH3:20])=[CH:22][CH:23]=3)=[O:27])[S:11][C:7]=2[C:6]([CH2:13][N:14]2[CH2:19][CH2:18][O:17][CH2:16][CH2:15]2)=[CH:5][CH:4]=1

Participants

4

Reactant 2

HCID 27600835-Methylthiophene-2-carbonyl chlorideHCID 22283216HCID 22283216, compound

Product 1

HCID 86584905HCID 86584905, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

Using 4-methoxy-7-morpholin-4-ylmethyl-benzothiazol-2-ylamine and 5-methyl-thiophene-2-carboxylic acid chloride in pyridine the title compound was obtained as a yellow solid (53% yield), MS: m/e=404.4 (M+H+).

Sources & evidence

ORD record
ord-ad1b3d5d35f34b1693e7b5c6b9af3386
Source dataset
uspto-grants-2008_01
Patent number
US07317007B2

Reaction notes

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