Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Chlorophenylboronic acid → 5-Methyl-thiophene-2-carboxylic acid [7-(2-chloro-phenyl)-4-methoxy-benzothiazol-2-yl]-amide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Chlorophenylboronic acid | HCID 2734322 | — |
| 반응물 | 5-Methyl-thiophene-2-carboxylic acid (4-methoxy-7-iodo-benzothiazol-2-yl)-amide | HCID 86584906 | — |
| 생성물 | 5-Methyl-thiophene-2-carboxylic acid [7-(2-chloro-phenyl)-4-methoxy-benzothiazol-2-yl]-amide | HCID 86584907 | 80% |
반응 단계
5-Methyl-thiophene-2-carboxylic acid [7-(2-chloro-phenyl)-4-methoxy-benzothiazol-2-yl]-amide is synthesized from 5-methyl-thiophene-2-carboxylic acid (7-iodo-4-methoxy-benzothiazol-2-yl)-amide (100 mg, 0.23 mmol) and 2-chlorophenylboronic acid (54 mg, 0.35 mmol) using the general procedure A as a light yellow solid in 80% yield. MS: m/e=415 (M+H+).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07317007B2 |
| 출처 데이터셋 | uspto-grants-2008_01 |
| ORD ID | ord-58a63ce356c24d4d9ec57c42ada38964 |
| 출처 메모 | uspto-grants-2008_01 |