HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(4-Benzyloxy-3-nitro-phenyl)-morpholine → 2-amino-4-(4-morpholinyl)Phenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(4-Benzyloxy-3-nitro-phenyl)-morpholine | HCID 22283345 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 2-amino-4-(4-morpholinyl)Phenol | HCID 22283062 | 96% |
Reaction Steps
Catalytic hydrogenation of 4-(4-benzyloxy-3-nitro-phenyl)-morpholine (5 g, 16 mmol) in dichloromethane (500 ml) and ethanol (500 ml) using palladium on carbon (500 mg, 10%) afforded the title compound as a grey solid (96%), MS: m/e=194(M+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07317007B2 |
| Source dataset | uspto-grants-2008_01 |
| ORD ID | ord-927bb99a42ed4ffbb13d87382d1699bc |
| Source note | uspto-grants-2008_01 |