HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(Chloromethyl)-5-methyl-1,2-oxazole → HCID 10160022, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(Chloromethyl)-5-methyl-1,2-oxazole | HCID 2735763 | — |
| Reactant | HCID 14631438 | HCID 14631438 | — |
| Product | HCID 10160022 | HCID 10160022 | 22% |
Reaction Steps
Methyl-2-tert-butoxycarbonylamino-3-(3,5-dibromo-4-hydroxyphenyl)propionate (0.035 mmol) was coupled with 3-chloromethyl-5-methylisoxazole and hydrolyzed using the method described in “General procedure for the preparation of Examples 8-22”. This gave 22% yield of 2-amino-3-[3,5-dibromo-4-(5-methylisoxazol-3-ylmethoxy)phenyl]propionic acid. LC/MS (electrospray): m/z 433 (M−1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07319096B2 |
| Source dataset | uspto-grants-2008_01 |
| ORD ID | ord-45badf0e87b746dca198e85707c4a9bc |
| Source note | uspto-grants-2008_01 |