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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2250983Generated: October 31, 2026

alpha-Bromo-o-fluorotoluene → HCID 10297430, compound

https://huagongshe.com/reaction/2250983

Reaction equation

Participants

RoleNameHCIDCharge
Reactantalpha-Bromo-o-fluorotolueneHCID 67968—
ReactantHCID 14631438HCID 14631438—
ProductHCID 10297430HCID 1029743010%

Reaction Steps

Methyl-2-tert-butoxycarbonylamino-3-(3,5-dibromo-4-hydroxyphenyl)propionate (0.035 mmol) was coupled with 1-bromomethyl-2-fluorobenzene and hydrolyzed using the method described in “General procedure for the preparation of Examples 8-22”. This gave 10% yield of 2-amino-3-[3,5-dibromo-4-(2-fluorobenzyloxy)phenyl]propionic acid. LC/MS (electrospray): m/z 446 (M−1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07319096B2
Source datasetuspto-grants-2008_01
ORD IDord-f3ffa7301dba459c861a7c1bc853c67b
Source noteuspto-grants-2008_01