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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 225101Generated: October 25, 2026

Phosphonic acid → 4-Methyl-2-methylene valeric acid

https://huagongshe.com/reaction/225101

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhosphonic acidHCID 407—
Reactant2-(Hydroxymethyl)-4-methylpentanoic acidHCID 11789343—
Product4-Methyl-2-methylene valeric acidHCID 168659—

Reaction Steps

The compounds of formula I can be prepared using as a starting material 2-(hydroxymethyl)-4-methylpentanoic acid. Heating the starting material with phosphonic acid yields 4-methyl-2-methylenepentanoic acid which can in turn be reacted with a thio acid having the formula

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04235885
Source datasetuspto-grants-1980_11
ORD IDord-033247e2a79a440599d16fa454dc8557
Source noteuspto-grants-1980_11