5-Bromo-7-chloroindoline → HCID 10296369, compound

Participants

Reaction Steps

Prepared in a similar fashion as described for Example 413 using 3,5-dichloro-1-(1-ethylpropyl)-2(1H)-pyrazinone and 5-bromo-7-chloroindoline as the starting materials. mp 156-157° C.; 1H NMR (300 MHz, CDCl3) δ 7.25 (d, J=1.8 Hz, 1H), 7.19 (d, J=2.9 Hz, 1H), 6.71 (s, 1H), 4.75-4.69 (m, 1H), 4.27 (t, J=7.9 Hz, 2H), 3.07 (t, J=8.1 Hz, 2H), 1.78-1.51 (m, 4H), 0.81 (t, J=7.3 Hz, 6H); HRMS (ESI) calcd for C17H19N3OBrCl2 (M+H)+: 430.0089; Found m/z 430.0106.

Provenance & Evidence