反应详情

A solution of 2-oxo-cycloheptanecarboxylic acid methyl ester (5 g, 29.4 mmol) and 2H-pyrazol-3-ylamine (2.44 g, 29.4 mmol) in acetic acid (5 mL) was heated at 100° C. for 1 hour and resulted in the formation of a colorless precipitate. The solid was collected via filtration and washed with ethanol and ethyl ether to give 6,7,8,9-tetrahydro-5H-1,4,10a-triaza-cyclohepta[f]inden-10-ol (5 g, 85% yield). The product was used without further purification.

1. customresulted in the formation of a colorless precipitate
2. filtrationThe solid was collected via filtration
3. washwashed with ethanol and ethyl ether