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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2251112Generated: November 3, 2026

1-Bromo-3-chloropropane → 9-[4-(3-Chloro-propoxy)-phenyl]-5,6,7,8-tetrahydro-pyrazolo[5,1-b]quinazoline

https://huagongshe.com/reaction/2251112

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Bromo-3-chloropropaneHCID 8006—
Reactant10-[4-(3-chloro-propoxy)-phenyl]-6,7,8,9-tetrahydro-5H-1,4,10a-triaza-cyclohepta[f]indeneHCID 58587706—
Reactant4-(5,6,7,8-Tetrahydro-pyrazolo[5,1-b]quinazolin-9-yl)-phenolHCID 136361022—
Product9-[4-(3-Chloro-propoxy)-phenyl]-5,6,7,8-tetrahydro-pyrazolo[5,1-b]quinazolineHCID 69255787—

Reaction Steps

Using the method described for the preparation of 10-[4-(3-chloro-propoxy)-phenyl]-6,7,8,9-tetrahydro-5H-1,4,10a-triaza-cyclohepta[f]indene, the reaction of 4-(5,6,7,8-tetrahydro-pyrazolo[5,1-b]quinazolin-9-yl)-phenol and 1-bromo-3-chloropropane provided the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07319103B2
Source datasetuspto-grants-2008_01
ORD IDord-2de8afba809e402c87f9afc9c9f5d11b
Source noteuspto-grants-2008_01